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Community cancer dusters are viewed quite differently by citizen activists and by epidemio

logists. Environmentalists and concerned local residents, for instance, might immediately suspect environmental radiation as the culprit when a high incidence of cancer cases occurs near a nuclear facility. Epidemiologists, in contrast, would be more likely to say that the incidences were "inconclusive" or the result of pure chance. And when a breast cancer survivor, Lorraine Pace, mapped 20 breast cancer cases occurring in her West Islip, Long Island, community, her rudimentary research efforts were guided more by hope—that a specific environmental agent could be correlated with the cancers—than by scientific method.

When epidemiologists study clusters of cancer cases and other noncontiguous conditions such as birth defects or miscarriage, they take several variables into account, such as background rate (the number of people affected in the general population) , duster size, and specificity (any notable characteristics of the individual affected in each case). If a cluster is both large and specific, it is easier for epidemiologists to assign blame. Not only must each variable be considered on its own, but it must also be combined with others. Lung cancer is very common in the general population. Yet when a huge number of cases turned up among World War II shipbuilders who had all worked with asbestos, the size of the cluster and the fact that the men had similar occupational asbestos exposures enabled epidemiologists to assign blame to the fibrous mineral.

Although several known carcinogens have been discovered through these kinds of occupational or medical clusters, only one community cancer duster has ever been traced to an environmental cause. Health officials often discount a community's suspicion of a common environmental cause because citizens tend to include cases that were diagnosed before the afflicted individuals moved into the neighborhood. Add to this is the problem of cancer's latency. Unlike an infectious disease such as cholera, which is caused by a recent exposure to food or water contaminated with the cholera bacterium, cancer may have its roots in an exposure that occurred 10 to 20 years earlier.

Do all these caveats mean that the hard work of Lorraine Pace and other community activists is for nothing? Not necessarily. Together with many other reports of breast cancer clusters on Long Island, the West Islip situation highlighted by Pace has helped epidemiologists lay the groundwork for a well-designed scientific study.

The "hope" mentioned in Paragraph 1 refers specifically to Pace's desire to______.

A.help reduce the incidence of breast cancer in future generations

B.improve her chances of surviving breast cancer

C.determine the cause responsible for her own breast cancer case

D.identify a particular cause for the breast cancer cases in West Islip

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更多“Community cancer dusters are v…”相关的问题

第1题

ABO血型和器官移植成功率之间的关系错误的是A、ABO血型不配合同种抗体会引起血管内皮损伤B、在移植

ABO血型和器官移植成功率之间的关系错误的是

A、ABO血型不配合同种抗体会引起血管内皮损伤

B、在移植物内形成血栓导致急性移植物排斥反应

C、O型供者可以供给各种血型的患者

D、A2亚型供者移植给0型受者可以获得同型移植的效果

E、ABO血型不合对肝脏移植是绝对禁忌

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第2题

ABO血型检查可应用于A、输血B、新生儿溶血病的检查C、器官移植D、ABO血型与疾病之间的关联E、以上都是

ABO血型检查可应用于

A、输血

B、新生儿溶血病的检查

C、器官移植

D、ABO血型与疾病之间的关联

E、以上都是

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第3题

关于ABO血型系统正确的观点是A、ABO血型系统存在于人体各种细胞膜上B、ABO血型系统抗体多为不完全

关于ABO血型系统正确的观点是

A、ABO血型系统存在于人体各种细胞膜上

B、ABO血型系统抗体多为不完全抗体

C、ABO血型系统只存在A和B两种抗原

D、是人类血型系统中抗原免疫原性最强的一个血型系统

E、ABO血型系统有5种基因型、4种表现型

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第4题

器官移植患者急性排斥反应的主要原因是A、ABO血型抗体不合B、HLA-Ⅰ类抗体不合C、受者曾做过某种同种

器官移植患者急性排斥反应的主要原因是

A、ABO血型抗体不合

B、HLA-Ⅰ类抗体不合

C、受者曾做过某种同种移植

D、慢性免疫性炎症

E、细胞免疫应答

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第5题

下列说法错误的是:_____

A、ABO血型存在天然抗体

B、新生儿血液中尚无ABO血型系统的抗体

C、天然ABO血型抗体多为IgM,可以通过胎盘

D、Rh血型抗体多为IgG,可以通过胎盘

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第6题

ABO血型系统与Rh血型系统的不同点在于()

A.ABO血型系统含有天然抗体

B.Rh血型系统不含有抗Rh的天然抗体

C.ABO血型系统中天然抗体多为IgM

D.Rh血型系统中的抗体多为IgG

E.ABO血型系统中抗体多为IgG

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第7题

ABO血型和器官移植成功率之间的关系错误的是()

A.BO相容供肝肝移植术比较,5年生存率无显著差异。

B. 在移植物内形成血栓导致急性移植物排斥反应

C. O型供者可以供给各种血型的患者

D. A亚型供者移植给O型受者可以获得同型移植的效果

E. ABO血型不合对肝脏移植是绝对禁忌

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第8题

器官移植的配型主要依据是()。

A.ABO血型

B.HLA血型

C.Rh血型

D.MN血型

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第9题

人体ABO血型系统存在天然抗体。()

人体ABO血型系统存在天然抗体。()

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